HORDB

ID: hor000348
Uniprot ID: Q1DH34
Protein name: AST-5
Gene name: NA
Organism: Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Family: Allatostatin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Stegomyia (subgenus), Aedes (genus), Aedini (tribe), Culicinae (subfamily), Culicidae (family), Culicoidea (superfamily), Culicomorpha (infraorder), Nematocera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity
GO BP: GO:0007165 signal transduction
GO CC: NA

Sequence: VYEDKRLPNRYNFGL
Length: 15(180-194)
Propeptide: MRPSTTPMVLLSYLAFVLCLACVAYGSSALGSSSGTSDQSLFGGGAGGGGGSASAESDIGDDRGQQEISQATFQHMLAVRSPKYNFGLGKRRYIIEDVPGAKRLPHYNFGLGKRARNNLLEYDDDSAPSWSEDYSSLIPRDGLDYDGDKDKSAEKRASAYRYHFGLGKRRVYDFGLGKRVYEDKRLPNRYNFGLGRR
Signal peptide: MRPSTTPMVLLSYLAFVLCLACVAYGSSA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000348_AF2.pdb

hor000348_ESM.pdb

Mass:	213401	Formula:	C86H130N24O24
Absent amino acids:	ACHIMQSTW	Common amino acids:	LNRY
pI:	9.14	Basic residues:	3
Polar residues:	5	Hydrophobic residues:	4
Hydrophobicity:	-112.67	Boman Index:	-4668
Half-Life:	100 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	71.33
Instability Index:	2598.67	Extinction Coefficient cystines:	2980
Absorbance 280nm:	212.86